In Development
AmPep
New generation antimicrobial peptides: aminoisoquinoline-based tryptophan bioisosteres.
Overview
We seek to develop a novel tryptophan mimic to probe tryptophan functions in, and to develop effective antimicrobial peptides to combat antimicrobial resistance in Sub-Saharan Africa.
Preliminary Study
Ozomarisi, H.E.; Sharpe, K.T.; Outlaw, V.K. A Synthetic Route to Highly Substituted 1-Aminonaphthalenes from Readily Available Benzaldehydes. J. Org. Chem. 2024, 89, 1310–1314.
doi.org/10.1021/acs.joc.3c02324Interested in AmPep?
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